"Murder Drones" takes place on Copper 9, an Earth type planet owned by the JC Jenson corporation where worker drones mine for resources. A core collapse, of the planet, caused by JC Jenson's employees, wipes out all life, leaving only worker drones. These drones face the threat of "Disassembly Drones" (Murder Drones) sent to exterminate them, leading to a society of worker drones living in fear behind every blast door. The series follows Uzi, a teenage worker drone, who forms an alliance with two Murder Drones, N and V, to uncover the truth about their origins and fight for her kind.